Tris DBA
Chemical Name: Tris(dibenzylideneacetone) dipalladium
Biological Activity
Tris DBA is a N-myristoyltransferase-1 (NMT-1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. Exhibits antiproliferative activity against melanoma cells in vitro and in vivo. Also used as a cyclization catalyst.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Tris(Dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo.
Bhandarkar et al.
Clin.Cancer Res., 2008;14:5743
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