Vialinin A

Catalog # Availability Size / Price Qty
4988/1
Cat.No. 4988 - Vialinin A | C34H26O8 | CAS No. 858134-23-3
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Description: Inhibitor of USP4 and USP5/IsoT

Chemical Name: 1,1'-(4,4'',5',6'-Tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl) benzeneacetic acid ester

Purity: ≥98%

Product Details
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Biological Activity

Inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 values are 1.5, 5.9 and 22.3 μM, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF-α (IC50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells.

Technical Data

M.Wt:
562.57
Formula:
C34H26O8
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
858134-23-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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