ZM 306416 hydrochloride

Catalog # Availability Size / Price Qty
2499/1
2499/10
ZM 306416 hydrochloride | CAS No. 196603-47-1 | VEGF Receptor Inhibitors
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Description: Inhibitor of VEGF receptor tyrosine kinase

Chemical Name: 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride

Purity: ≥99%

Product Details
Citations (5)
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Biological Activity

Inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 μM respectively) and displays > 3-fold selectivity over FGFR-1. Orally active in vivo.

Technical Data

M.Wt:
370.21
Formula:
C16H13N3O2FCl.HCl
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
196603-47-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Product Datasheets

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Citations for ZM 306416 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for ZM 306416 hydrochloride include:

5 Citations: Showing 1 - 5

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