T Cell-Based Therapies eBook

This eBook provides an overview of several biological and manufacturing challenges facing the development and production of T cell therapies. It follows with examples of how Bio-Techne products and services can address these challenges at each stage of the process.

Download your copy of this eBook to learn about:

Biological Challenges

• T Cell Exhaustion
• Checkpoint Blockade
• Immunosuppressive TME
• Cell Migration
• Tumor Heterogeneity
• Monitoring Efficacy and Toxicity
• T Cell Subsets and Capabilities

Manufacturing Challenges

• Scaling Up
• Cell Characterization
• Customization
• Outsourcing and CDMO
• Raw Materials Qualification
• Transition to GMP
• Quality

Process Stages

• Isolating T Cell Populations
• Cell Activation and Expansion
• Cell Engineering
• Cell Characterization
• Monitoring Efficacy and Toxicity