CHL-1/L1CAM-2 Proteins and Enzymes

CHL-1 is a transmembrane glycoprotein that is a member of the L1 family of cell adhesion molecules. It promotes neurite outgrowth, neuronal survival and enhances integrin-mediated cell migration toward extracellular matrix proteins. In humans, CHL-1 is a candidate gene for 3p-syndrome-associated mental impairment.