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1 result for "Class II Histone Deacetylases Degraders" in Products
Class II Histone Deacetylases Degraders
HDAC classification
| Superfamily | Family | Class | Subclass | Protein (human) |
|---|---|---|---|---|
| Arginase/deacetylase superfamily | Histone deacetylase family | Class I | HDAC1, HDAC2, HDAC3, HDAC8 | |
| Class II | Class IIa | HDAC4, HDAC5, HDAC7, HDAC9 | ||
| ClassIIb | HDAC6, HDAC10 | |||
| Class IV | HDAC11 | |||
| Deoxyhypusine synthase like NAD/FAD-binding domain superfamily | Sir2 regulator family | Class III | I | SIRT1, SIRT2, SIRT3 |
| II | SIRT4 | |||
| III | SIRT5 | |||
| IV | SIRT6, SIRT7 |
Potent and selective HDAC4 Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((3R,26S)-26-(tert-Butyl)-3-methyl-1,24-dioxo-5-propyl-1-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-10,13,16,19,22-pentaoxa-2,5,25-triazaheptacosan-27-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
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