FANCC cDNA Clones

The Fanconi anemia group C protein (FANCC) is a member of the Fanconi anemia complementation. FANCC functions as a cell cycle checkpoint to delay the onset of apoptosis and promotes homologous recombination repair of damaged DNA. FANCC may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in FANCC portein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in many congenital malformations and predisposition to malignant formations.

FANCC antibodies are useful for DNA repair studies and cell cycle research.