MAMLD1 Proteins and Enzymes

MAMLD1, or Mastermind-like domain-containing protein 1, contains a 83 kDa, 106 kDa, and 80 kDa isoform, and is involved in transcription and acts as a co-activator for the HES3 promoter. Current research is being conducted on MAMLD1 and its relation to x-linked hypospadias type 2, myopathy, and spermatic cord torsion. The protein has no known interactions with any other proteins, but it is linked to the Notch-HLH transcription pathway, regulation of DNA-dependent transcription, and male gonad development.