Neuroplastin Proteins and Enzymes

Neuroplastin (NPTN; also stromal cell-derived receptor 1 and Np55) is a 52 - 57 kDa member of the Ig-superfamily. Neuroplastin is widely expressed and likely serves as a cell adhesion molecule in multiple tissues. Human Neuroplastin is 282 amino acids (aa) in length. It is a type I transmembrane glycoprotein that contains two Ig-like domains (aa 32 - 119 and 122 - 213) and a 38 aa cytoplasmic region (aa 245 - 282).

There is a brain-enriched 65 kDa form of Neuroplastin (Np65) that negatively ...