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1 result for "PPM1D Small Molecules and Peptides" in Products
PPM1D Small Molecules and Peptides
Wip1 is a p53-inducible protein phosphatase that dephosphorylates p38 MAPK. Dephosphorylation of p38 MAPK prevents phosphorylation of p53 at S46, thereby preventing p53-dependent apoptosis.
Potent and selective allosteric inhibitor of Wip1 phosphatase
| Chemical Name: | 5-[[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cycloprpylamino)-2-oxoethyl]-2-thiophenecarboxamide |
| Purity: | ≥98% |
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