RPL3 Proteins and Enzymes

RPL3, also known as 60S ribosomal protein L3, is a 46 kDa 403 amino acid protein found in the cytoplasm. The primary function of RPL3 is believed to contribute to tat-mediated transactivation. Research is currently being conducted on RPL3 in relation to Treacher Collins syndrome, kidney disease, esophageal carcinoma, ovarian carcinoma, esophagitis, colon cancer, prostate cancer, carcinoma, prostatitis and malaria. The gene has been linked to the pathogenesis, innervation, translation, transport and metabolism of mRNA pathways where it interacts with RPS3, RPL4, RPL8, RPL11, and RPL12.