L-690,488
Chemical Name: 1-[(4-Hydroxyphenoxy)ethylidene]bis[phosphinylidynebis(oxymethylene)]-2,2-dimethylpropanoate
Purity: ≥98%
Biological Activity
L-690,488 is a cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330 (Cat. No. 0681); penetrates cells more effectively than its metabolite.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.
Atack et al.
J.Pharmacol.Exp.Ther., 1994;270:70 -
Stimulatory effect of Li on glucose transport in rat adipocytes is not mediated by elevation of IP1.
Chen et al.
Am.J.Physiol., 1998;275:E272
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Citation for L-690,488
The citations listed below are publications that use Tocris products. Selected citations for L-690,488 include:
1 Citation: Showing 1 - 1
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LtpD is a novel Legionella pneumophila effector that binds phosphatidylinositol 3-phosphate and inositol monophosphatase IMPA1.
Authors: Harding Et al.
Mol Cancer 2013;81:4261
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