L-690,488

Tocris Bioscience | Catalog # 0682

Cell permeable prodrug of the IMPase inhibitor L-690,330 (Cat. No. 0681)
Tocris Bioscience
Discontinued Product
0682 has been discontinued. View all Inositol Lipid Inhibitors products.

Key Product Details

Description

Cell permeable prodrug of the IMPase inhibitor L-690,330 (Cat. No. 0681)
View all Inositol Lipid Inhibitors »

Product Description

L-690,488 is a cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330 (Cat. No. 0681); penetrates cells more effectively than its metabolite.

Licensing Information

Sold with the permission of Merck Sharp and Dohme Ltd.

Product Specifications for L-690,488

Molecular Weight

754.70

Formula

C32H52O16P2

Storage

Store at -80°C

Purity

≥98% (HPLC)

Chemical Name

1-[(4-Hydroxyphenoxy)ethylidene]bis[phosphinylidynebis(oxymethylene)]-2,2-dimethylpropanoate

CAS Number

142523-14-6

PubChem ID

5132514

InChI Key

LOTSPVPQHAUHCE-UHFFFAOYSA-N

SMILES

OC1=CC=C(OC(P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)(C)P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 75.47 100
Ethanol 75.47 100

Preparing Stock Solutions for L-690,488

The following data is based on the product molecular weight 754.70.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.33 mL 6.63 mL 13.25 mL
5 mM 0.27 mL 1.33 mL 2.65 mL
10 mM 0.13 mL 0.66 mL 1.33 mL
50 mM 0.03 mL 0.13 mL 0.27 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for L-690,488

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for L-690,488

For research use only

Related Research Areas

Ion Channels and Regulators

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