5,7-Dichlorokynurenic acid sodium salt
Chemical Name: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt
Biological Activity5,7-Dichlorokynurenic acid sodium salt is a sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286), a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site.
Baron et al.
Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor.
Moore et al.
Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I, 1990;
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