5,7-Dichlorokynurenic acid

Key Product Details

Product Description

5,7-Dichlorokynurenic acid is a potent antagonist at the glycine site of the NMDA receptor (K_i = 79 nM vs. [³H]-glycine).

Sodium Salt also available.

Product Specifications for 5,7-Dichlorokynurenic acid

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 5,7-Dichlorokynurenic acid

The following data is based on the product molecular weight 258.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

6 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.88 mL	19.38 mL	38.75 mL
5 mM	0.78 mL	3.88 mL	7.75 mL
10 mM	0.39 mL	1.94 mL	3.88 mL
50 mM	0.08 mL	0.39 mL	0.78 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 23 publications citing the usage of this product.

• Moore Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor. Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I
• Baron Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site. Mol.Pharmacol. 1990 PMID: 2172769

Product Documents for 5,7-Dichlorokynurenic acid