Potent antagonist at the glycine site of the NMDA receptor (Ki
= 79 nM vs. [3
H]-glycine). Sodium salt
(Cat. No. 3698) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site.
Baron et al.
Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor.
Moore et al.
Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I, 1990;
The citations listed below are publications that use Tocris products. Selected citations for 5,7-Dichlorokynurenic acid include:
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