ABT 724 trihydrochloride

Catalog # Availability Size / Price Qty
2214/10
2214/50
ABT 724 trihydrochloride | CAS No. 587870-77-7 | Dopamine D4 Receptor Agonists
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Description: Potent and selective D4 partial agonist; proerectile

Chemical Name: 2-[[4-(2-Pyridinyl)-1-piperazinyl]methyl]-1H-benzimidazole trihydrochloride

Purity: ≥99%

Product Details
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Biological Activity

Potent dopamine D4 receptor partial agonist (EC50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D2 receptors (EC50 > 10 μM). Selective in rats in vivo; produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.

Technical Data

M.Wt:
402.75
Formula:
C17H19N5.3HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
587870-77-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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