ACET

  ( 1 citations )    
Product Datasheet
Catalog Number:2728
Chemical Name:(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione
Product Details
Citations (1)
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Biological Activity
Potent and selective GluK1 (formally GluR5) containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluK2 (formally GluR6) containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data
  • M.Wt:
    429.45
  • Formula:
    C20H19N3O6S
  • Solubility:
    Soluble to 20 mM in 3eq. NaOH
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    936095-50-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for ACET include:

1 Citations: Showing 1 - 1

  1. LTD expression is independent of glutamate receptor subtype.
    Authors: Granger and Nicoll
    J Virol  2014;6:15

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