AGN 192403 hydrochloride

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AGN 192403 hydrochloride | CAS No. 1021868-90-5 | Imidazoline 1 (I1) Receptor Ligands
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Description: I1 selective ligand
Alternative Names: BRD4780

Chemical Name: (±)-2-endo-Amino-3-exo-isopropylbicyclo[2.2.1]heptane hydrochloride

Product Details
Citations (2)

Biological Activity

AGN 192403 hydrochloride is an i1 imidazoline binding site selective ligand with a potency at I1 comparable to moxonidine, but devoid of affinity for adrenoceptors and the I2 binding site. Causes none of the physiological responses associated with the I1 binding site in animal models. Also binds TMED9 cargo receptor. Releases MUC1-fs from TMED9 containing vesicles in kidney cells bearing MUC1 gene mutation

Technical Data

Soluble to 100 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Citations for AGN 192403 hydrochloride

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