ARN 726

Catalog # Availability Size / Price Qty
5861/50
5861/10
ARN 726 | CAS No. 1628343-77-0 | General Laboratory Research Reagent
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Description: Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe

Chemical Name: 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate

Purity: ≥98%

Product Details
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Biological Activity

Potent N-acylethanolamine acid amidase (NAAA) inhibitor (IC50 values are 27 nM and 63 nM for human and rat NAAA, respectively). Displays anti-inflammatory effects in human macrophages ex vivo and mouse models of lung inflammation and arthritis. Also used as NAAA activity-based protein profiling (ABPP) probe to detect NAAA in cell lysates or intact cells.

Technical Data

M.Wt:
268.35
Formula:
C14H24N2O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1628343-77-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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