Arvanil (CAS 128007-31-8): R&D Systems
Catalog Number: 1354
Chemical Name: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5Z,8Z,11Z,14Z-eicosatetraenamide
Biological Activity
Cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist (Ki values are 0.5 and 0.3 μM respectively). Also inhibits the anandamide transporter (IC50 = 3.6 μM). Analgesic, vasodilatory and anti-inflammatory in vivo.
Technical Data
  • M.Wt:
    439.64
  • Formula:
    C28H41NO3
  • Solubility:
    Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
  • Purity:
    >98%
  • Storage:
    Desiccate at -20°C
  • CAS No:
    128007-31-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide.
    Di Marzo et al.
    Eur.J.Pharmacol., 2000;406:363
  2. Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 receptors.
    Melck et al.
    Biochem.Biophys.Res.Commun., 1999;262:275
  3. New perspectives on enigmatic vanilloid receptors.
    Szallasi and Di Marzo
    Trends Neurosci., 2000;23:491

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