BMS 195614

  ( 3 citations )    
Product Datasheet
Catalog Number:3660
Alternate Names:BMS614
Chemical Name:4-[[[5,6-Dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoic acid
Product Details
Citations (3)
Reviews
Biological Activity
Neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5 nM). Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. Antagonizes agonist-induced coactivator (CoA) recruitment.
Technical Data
  • M.Wt:
    448.51
  • Formula:
    C29H24N2O3
  • Solubility:
    Soluble to 25 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    253310-42-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BMS 195614 include:

3 Citations: Showing 1 - 3
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  1. Retinoic acid reduces migration of human breast cancer cells: role of retinoic acid receptor beta.
    Authors: Flamini Et al.
    J Cell Mol Med  2014;18:1113
  2. Retinoic acid inhibits CD25+ dendritic cell expansion and γδ T-cell activation in experimental autoimmune uveitis.
    Authors: Liang Et al.
    Invest Ophthalmol Vis Sci  2013;54:3493
  3. Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.
    Authors: Johansson Et al.
    Nat Commun  2013;4:2175

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