BRD 7389

Catalog # Availability Size / Price Qty
4037/10
4037/50
RSK Inhibitors Small Molecule
1 Image
Description: Ribosomal S6 kinase inhibitor

Chemical Name: 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione

Purity: ≥97%

Product Details
Citations (1)
Reviews

Biological Activity

Ribosomal S6 kinase (RSK) inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in terminally differentiated pancreatic α-cells.

Technical Data

M.Wt:
366.41
Formula:
C24H18N2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
376382-11-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Small molecule inducers of Ins expression in pancreatic alpha cells.
    Fomina-Yadlin et al.
    Proc.Natl.Acad.Sci. USA, 2010;107:15099

Product Datasheets

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Reconstitution Calculator

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Citation for BRD 7389

The citations listed below are publications that use Tocris products. Selected citations for BRD 7389 include:

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