BRD 7389

Key Product Details

Product Description

BRD 7389 is a ribosomal S6 kinase (RSK) inhibitor (IC₅₀ values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in terminally differentiated pancreatic α-cells.

Product Specifications for BRD 7389

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BRD 7389

The following data is based on the product molecular weight 366.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.73 mL	13.65 mL	27.29 mL
5 mM	0.55 mL	2.73 mL	5.46 mL
10 mM	0.27 mL	1.36 mL	2.73 mL
50 mM	0.05 mL	0.27 mL	0.55 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Fomina-Yadlin Small molecule inducers of Ins expression in pancreatic alpha cells. Proc.Natl.Acad.Sci.U.S.A. 2010 PMID: 20696901

Product Documents for BRD 7389