Translation Regulation

R&D Systems offers quality products for the study of protein synthesis and translational regulation. We offer products for eIFs, heterotrimeric initiation complexes that form on the ribosome during protein synthesis. Each eIF serves a distinct function during protein synthesis to help attach, assemble, and drive the ribosome along the mRNA. Studies show that eIF activity plays an important role in cell cycle progression, tumorigenesis, embryonic development, nuclear export, and synaptic plasticity. In addition, we offer products targeting other molecules that are involved in the initiation (4EBP1) and inhibition of protein synthesis (MBD-3, PERK).