Budesonide

Tocris Bioscience | Catalog # 2671

Synthetic glucocorticoid; anti-inflammatory and chemopreventive
Tocris Bioscience
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Key Product Details

Description

Synthetic glucocorticoid; anti-inflammatory and chemopreventive

Product Description

Budesonide is a synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes.

Product Specifications for Budesonide

Molecular Weight

430.53

Formula

C25H34O6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

CAS Number

51333-22-3

PubChem ID

5281004

InChI Key

VOVIALXJUBGFJZ-KWVAZRHASA-N

SMILES

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3C[C@@H]5[C@](C(CO)=O)4OC(CCC)O5)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 43.05 100
Ethanol 21.52 50

Preparing Stock Solutions for Budesonide

The following data is based on the product molecular weight 430.53.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL
10 mM 0.23 mL 1.16 mL 2.32 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

Product Documents for Budesonide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Budesonide

For research use only

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