Budesonide

Catalog # Availability Size / Price Qty
2671/50
Glucocorticoid Receptor Compounds Small Molecule
1 Image
Description: Synthetic glucocorticoid; anti-inflammatory and chemopreventive

Chemical Name: (11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Purity: ≥98%

Product Details
Citations (3)
Reviews

Biological Activity

Synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes.

Technical Data

M.Wt:
430.53
Formula:
C25H34O6
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
51333-22-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease.
    Spencer et al.
    Drugs, 1995;50:854
  2. Modulation by budes. of DNA methylation and mRNA expression in mouse lung tumors.
    Pereira et al.
    Int.J.Cancer, 2006;120:1150
  3. Chemoprevention of pulmonary carcinogenesis by aerosolized budes. in female A/J mice.
    Wattenberg et al.
    Cancer Res., 2007;57:5489

Product Datasheets

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Citations for Budesonide

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