C 87

Catalog # Availability Size / Price Qty
5484/10
5484/50
Cat.No. 5484 - C 87 | C24H15ClN6O3S | CAS No. 332420-90-3
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Description: TNF-α inhibitor

Chemical Name: 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(4-chloro-3-nitrophenyl)hydrazone]

Purity: ≥98%

Product Details
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Reviews (1)

Biological Activity

TNF-α inhibitor (Kd = 110 nM for hTNF-α). Inhibits TNF-α-induced cytotoxicity in L929 fibroblast cells. Attenuates inflammation and increases survival in a mouse hepatitis model.

Technical Data

M.Wt:
502.93
Formula:
C24H15ClN6O3S
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
332420-90-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Works Well.
By Purnima Gupta on 01/10/2018
Species: Mouse

Used in Fibroblast cytotoxicity assay


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