20 results for "Cytokine Compounds" in Products
Cytokine Compounds
Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases.
Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune ...
Antifibrotic agent; regulates cytokine levels in vivo
| Chemical Name: | 5-methyl-1-phenyl-2(1H)-pyridinone |
| Purity: | ≥98% |
Binds cereblon; also TNF-α synthesis inhibitor
| Chemical Name: | N-(2,6-dioxo-3-piperidinyl)phthalimide |
| Purity: | ≥98% |
Macrophage migration inhibitory factor (MIF) inhibitor
| Chemical Name: | 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester |
| Purity: | ≥98% |
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
| Chemical Name: | 2-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl) 2-pyrazinecarboxylic acid hydrazide hydrochloride |
| Purity: | ≥98% |
Suppressor of MDK expression; inhibits PI 3-K signaling
| Chemical Name: | 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
| Purity: | ≥98% |
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
| Chemical Name: | 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione |
| Purity: | ≥98% |
Selective Syk kinase inhibitor
| Chemical Name: | 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate |
| Purity: | ≥98% |
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
| Chemical Name: | 4-Iodo-6-phenylpyrimidine |
| Purity: | ≥98% |
Cereblon binder; also TNF-α inhibitor and antiangiogenic
| Chemical Name: | 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
| Purity: | ≥98% |
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
| Alternate Names: | FOY |
| Chemical Name: | 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate |
| Purity: | ≥98% |
Immunomodulator; reduces production of pro-inflammatory cytokines
| Chemical Name: | 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid |
| Purity: | ≥98% |
MIF binder
| Chemical Name: | 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one |
| Purity: | ≥98% |
Immunomodulatory and antitumor compound
| Chemical Name: | 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone |
| Purity: | ≥98% |
Active metabolite binds CPSF3; Pro-drug
| Alternate Names: | TO-207 |
| Chemical Name: | N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride |
| Purity: | ≥98% |
Potent and selective IRAK4 inhibitor
| Chemical Name: | N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride |
| Purity: | ≥98% |
gp130 agonist; brain penetrant and neuroprotectant
| Chemical Name: | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Purity: | ≥98% |
NLRP3 inflammasome inhibitor
| Alternate Names: | JC121 |
| Chemical Name: | N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide |
| Purity: | ≥98% |
TIR-TIR interaction inhibitor
| Chemical Name: | 1-Methyl-2,5-bis[[[(1S)-2-methyl-1-(1-pyrrolidinylcarbonyl)propyl](3-phenylpropyl)amino]carbonyl]pyridinium iodide |
| Purity: | ≥98% |
TRAF6-Ubc13 interaction inhibitor
| Chemical Name: | 3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone |
| Purity: | ≥98% |
Potent NLRP3 inflammasome inhibitor
| Chemical Name: | 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione |
| Purity: | ≥95% |
