Calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+
-transporting ATPase with IC50
values of 0.15 and 0.35 μ
M respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Comparison of the calmodulin antagonists compound 48/80 and calmidazolium.
Effect of calmidazolium analogs on calcium influx in HL-60 cells.
Harper and Daly
Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells.
Peppiatt et al.
The citations listed below are publications that use Tocris products. Selected citations for Calmidazolium chloride include:
Showing Results 1 - 1 of 1