Calmidazolium chloride

Tocris Bioscience | Catalog # 2561

Calmodulin antagonist
Tocris Bioscience

Key Product Details

Description

Calmodulin antagonist

Alternative Names

R 24571
View all Calcium Binding Protein Modulator Antagonists »

Product Description

Calmidazolium chloride is a calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 μM respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.

Product Specifications for Calmidazolium chloride

Molecular Weight

687.70

Formula

C31H23Cl7N2O

Storage

Store at +4°C

Purity

≥95% (HPLC)

Chemical Name

1-[Bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride

CAS Number

57265-65-3

PubChem ID

644274

InChI Key

YGEIMSMISRCBFF-UHFFFAOYSA-M

SMILES

[Cl-].ClC1=CC=C(C=C1)C(N1C=C[N+](CC(OCC2=CC=C(Cl)C=C2Cl)C2=CC=C(Cl)C=C2Cl)=C1)C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 68.77 100
Ethanol 68.77 100

Preparing Stock Solutions for Calmidazolium chloride

The following data is based on the product molecular weight 687.70.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.45 mL 7.27 mL 14.54 mL
5 mM 0.29 mL 1.45 mL 2.91 mL
10 mM 0.15 mL 0.73 mL 1.45 mL
50 mM 0.03 mL 0.15 mL 0.29 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for Calmidazolium chloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Calmidazolium chloride

For research use only

Citations for Calmidazolium chloride

Customer Reviews for Calmidazolium chloride

There are currently no reviews for this product. Be the first to review Calmidazolium chloride and earn rewards!

Have you used Calmidazolium chloride?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card