Cardamonin

Catalog # Availability Size / Price Qty
2509/10
2509/50
Cat.No. 2509 - Cardamonin | C16H14O4 | CAS No. 19309-14-9
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Description: Inhibitor of NF-κB activation; anti-inflammatory

Chemical Name: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one

Purity: ≥98%

Product Details
Citations (3)
Reviews

Biological Activity

Chalone analog that display anti-inflammatory activity. Inhibits NO and PGE2 production from LPS- and IFN-γ-induced RAW cells and inhibits TXB2 production via the COX-1 and COX-2 pathways. Inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation.

Technical Data

M.Wt:
270.28
Formula:
C16H14O4
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
19309-14-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citations for Cardamonin

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3 Citations: Showing 1 - 3

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