Cardionogen 1
Chemical Name: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
Purity: ≥99%
Biological Activity
Wnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling.
Ni et al.
Chem.Biol., 2011;18:1658
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