Catalog Number: 4475
Chemical Name: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
Biological Activity
Wnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.
Technical Data
  • M.Wt:
    274.34
  • Formula:
    C13H14N4OS
  • Solubility:
    Soluble to 20 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    577696-37-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling.
    Ni et al.
    Chem.Biol., 2011;18:1658

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