Recombinant Human CBR3 His Protein

Novus Biologicals | Catalog # NBC1-28781

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-277 of Human CBR3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSSCSRVALV TGANRGIGLA IARELCRQFS GDVVLTARDV ARGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLNVLVNN AAVAFKSDDP MPFDIKAEMT LKTNFFATRN MCNELLPIMK PHGRVVNISS LQCLRAFENC SEDLQERFHS ETLTEGDLVD LMKKFVEDTK NEVHEREGWP NSPYGVSKLG VTVLSRILAR RLDEKRKADR ILVNACCPGP VKTDMDGKDS IRTVEEGAET PVYLALLPPD ATEPQGQLVH DKVVQNW

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

33 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CBR3 His Protein

SDS-PAGE: Recombinant Human CBR3 His Protein [NBC1-28781]

SDS-PAGE: Recombinant Human CBR3 His Protein [NBC1-28781]

SDS-Page: CBR3 Protein [NBC1-28781] - Carbonyl reductase 3, 33 kDa (297aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation, and Storage

NBC1-28781
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CBR3

Carbonyl reductase 3(CBR3) is one of several monomeric NADPH-dependent oxidoreductases. This protein catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It also contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. Some studies suggest that it mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy. Recombinant human CBR3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

carbonyl reductase (NADPH) 3, carbonyl reductase (NADPH) 3, EC 1.1.1.18410EC 1.1.1, carbonyl reductase [NADPH] 3, carbonyl reductase 3, EC 1.1.1.184, hCBR3, NADPH-dependent carbonyl reductase 3, SDR21C2, short chain dehydrogenase/reductase family 21C, member 2

Gene Symbol

CBR3

Additional CBR3 Products

Product Documents for Recombinant Human CBR3 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human CBR3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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