Ccd1/DIXDC1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-28983

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Between 225 and 275

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Ccd1/DIXDC1 Antibody - BSA Free

Ccd1/DIXDC1 Antibody

Immunoprecipitation:Ccd1/DIXDC1 AntibodyNBP3-28983] -

Immunoprecipitation:Ccd1/DIXDC1 AntibodyNBP3-28983] -Detection of human DIXDC1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-DIXDC1 antibody NBP3-28983 (lot NBP3-28983-1) used for IP at 6 µg/mg lysate. DIXDC1 was also immunoprecipitated by rabbit anti-DIXDC1 antibodies, and. For blotting immunoprecipitated DIXDC1, was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for Ccd1/DIXDC1 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Ccd1/DIXDC1

DIXDC1 (DIX domain containing 1/Dixin) is a 683 amino acid protein. It positively regulates the Wnt signaling pathway by activating WNT3A via DVL2. It is expressed ubiquitously but has higher expression in skeletal and cardiac muscle. WNT3A signaling increases DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation. DIXDC1 may play a role in breast cancer, breast carcinoma, endometrial cancer, epithelial neoplasia, schizophrenia, colon cancer, and neuroblastoma.

Long Name

Coiled-coil DIX1/DIX Domain Containing 1

Alternate Names

Dixdc1, Dixin, Kiaa1735

Gene Symbol

DIXDC1

Additional Ccd1/DIXDC1 Products

Product Documents for Ccd1/DIXDC1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Ccd1/DIXDC1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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