Home / NMDA Receptor Antagonists / CGP 39551

CGP 39551

Catalog #: 1409
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1409/10
1409/50
CGP 39551 | CAS No. 127910-32-1 | NMDA Receptor Antagonists
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Description: Potent, selective and competitive NMDA antagonist

Chemical Name: (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester

Purity: ≥98%

Product Details
Citations (2)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

CGP 39551 is a potent, selective and competitive NMDA antagonist (Ki = 310 nM for inhibition of [3H]-CPP binding in rat brain). Centrally active upon oral administration in vivo.

Technical Data

M.Wt:
237.19
Formula:
C8H16NO5P
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
127910-32-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for CGP 39551

The citations listed below are publications that use Tocris products. Selected citations for CGP 39551 include:

2 Citations: Showing 1 - 2

  1. Phasic D1 and tonic D2 DA receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal.
    Authors: Grieder Et al.
    Proc Natl Acad Sci U S A  2012;109:3101
  2. Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking.
    Authors: Bäckström and Hyytiä
    Neuropsychopharmacology  2006;31:778

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