Potent, selective and competitive NMDA antagonist (Ki
= 310 nM for inhibition of [3
H]-CPP binding in rat brain). Centrally active upon oral administration in vivo
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Effects of competitive NMDA receptor antagonists on excitatory amino-acid-evoked currents in mouse spinal cord.
D'Hooge et al.
CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-asparate receptor antagonists with oral activity.
Fagg et al.
Anticonvulsant and behavioural effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine.
Loscher and Honack
The citations listed below are publications that use Tocris products. Selected citations for CGP 39551 include:
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