Catalog Number: 4446
Chemical Name: 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate
Biological Activity
Inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.
Technical Data
  • M.Wt:
    382.39
  • Formula:
    C16H18N2O7S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >97%
  • Storage:
    Store at +4°C
  • CAS No:
    749872-43-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening.
    Bialkowska et al.
    Mol.Cancer Ther., 2011;10:2043

Have you used CID 5951923?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information