CMPDA

Catalog # Availability Size / Price Qty
4373/10
4373/50
CMPDA | CAS No. 380607-77-2 | AMPA Receptor Modulators
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Description: Positive allosteric modulator of GluA2 receptors

Chemical Name: N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide

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Biological Activity

Positive allosteric modulator of GluA2 receptors (EC50 values are 45.4 and 63.4 nM at GluA2i and GluA2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.

Technical Data

Formula:
C16H28N2O4S2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
380607-77-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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