6 results for "AMPA Receptor Modulators" in Products

AMPA Receptor Modulators

AMPA receptors are cation-permeable, ligand-gated ion channels. Like other members of this family, AMPA receptors are named based on a compound that was found to be selective for these receptors; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA). They consist of GluA1-4 subunits that assemble as homomers or heteromers to form functional receptors. Each subunit is encoded by a different gene, and alternative versions of the subunits may be produced by gene splicing. There is a ...

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Positive allosteric modulator of AMPA receptors; inhibits AMPA desensitization

Chemical Name: 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide
Purity: ≥98%
Positive allosteric modulator of AMPA receptors; inhibits AMPA desensitization
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AMPA potentiator

Chemical Name: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone
Purity: ≥98%
AMPA potentiator
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Positive allosteric modulator of AMPA receptors

Chemical Name: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one
Purity: ≥98%
Positive allosteric modulator of AMPA receptors
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Selective positive allosteric modulator of AMPA receptors

Chemical Name: N-[2-(4'-Cyano[1,1'-biphenyl]-4-yl)propyl]-2-propanesulfonamide
Purity: ≥98%
Selective positive allosteric modulator of AMPA receptors
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High affinity and selective negative modulator of AMPA receptors containing TARP-γ8

Chemical Name: 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one
Purity: ≥98%
High affinity and selective negative modulator of AMPA receptors containing TARP-γ8
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Positive allosteric modulator of AMPA receptors

Chemical Name: N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
Purity: ≥98%
Positive allosteric modulator of AMPA receptors
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