Chemical Name: (2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine
Biological ActivityPotent and selective non-peptide NK1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A potent nonpeptide antagonist of the substance P (NK1) receptor.
Snider et al.
The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation.
Lembeck et al.
Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury.
Bang et al.
Citation for CP 96345
The citations listed below are publications that use Tocris products. Selected citations for CP 96345 include:
1 Citation: Showing 1 - 1
Spinal blockage of P/Q- or N-type voltage-gated calcium channels modulates functional and symptomatic changes related to haemorrhagic cystitis in mice.
Authors: Silva Et al.
Br J Pharmacol 2015;172:924
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for CP 96345
There are currently no reviews for this product. Be the first to review CP 96345 and earn rewards!
Have you used CP 96345?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image