Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC50
values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (KB
= 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Synthesis of S-[3-(4(5)-imidazolyl)propyl]-N-[2-(4-[125I]-iodophenylethyl]isothiourea sulfate [125I]-iodophenpropit), a new probe for histamine H3 receptor binding sites.
Menge et al.
J.Labelled Comp.Radiopharm. XXXI, 1992;10:781
Potent antagonists at the L-AP4- and (1S, 3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.
Jane et al.
The effects of (RS)-α-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist.
Toms et al.
The citations listed below are publications that use Tocris products. Selected citations for CPPG include:
Showing Results 1 - 10 of 16