Cyanopindolol hemifumarate

Catalog # Availability Size / Price Qty
0993/10
0993/50
5-HT1A Receptor Antagonists Small Molecule
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Description: 5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist

Chemical Name: 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate

Purity: ≥98%

Product Details
Citations (4)
Supplemental Products
Reviews

Biological Activity

5-HT1A/1B antagonist with roughly equal affinity at each receptor; also a β-adrenoceptor antagonist.

Technical Data

M.Wt:
345.4
Formula:
C16H21N3O2.½C4H4O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
69906-86-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Identity of presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites.
    Engel et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1986;332:1
  2. Atypical responses of rat ileum to pindolol, cyanopindolol and iodocyanopindolol.
    Hoey et al.
    Br.J.Pharmacol., 1996;117:712
  3. Characterization of a 5-HT1B receptor on CHO cells: functional responses in the absence of radioligand binding.
    Giles et al.
    Br.J.Pharmacol., 1996;117:1119
  4. Interaction of dihydroalprenolol and cyanopindolol with atypical β-adrenoceptors in guinea-pig ileum.
    Blue et al.
    Br.J.Pharmacol., 1989;96:246P

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Citations for Cyanopindolol hemifumarate

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