Cyanopindolol hemifumarate

  ( 4 citations )    
Product Datasheet
Catalog Number:0993
Chemical Name:4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate
Product Details
Citations (4)
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Reviews
Biological Activity
5-HT1A/1B antagonist with roughly equal affinity at each receptor; also a β-adrenoceptor antagonist.
Technical Data
  • M.Wt:
    345.4
  • Formula:
    C16H21N3O2.½C4H4O4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    69906-86-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cyanopindolol hemifumarate include:

4 Citations: Showing 1 - 4
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  1. Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling.
    Authors: Gautam Et al.
    Mol Cancer  2016;15:75
  2. Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation.
    Authors: Kaya Et al.
    J Pharmacol Exp Ther  2009;329:350
  3. ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta.
    Authors: Brahmadevara Et al.
    Br J Pharmacol  2004;142:781
  4. Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
    Authors: Geerts Et al.
    Br J Pharmacol  1999;127:1327

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