Catalog Number: 3116
Chemical Name: 7-Nitro-5-(trifluoromethyl)-2-benzothiazolecarboxamide-3-oxide
Biological Activity
Selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC50 = 500 nM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in DMSO and to 10 mM in ethanol
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Ligand discovery and virtual screening using the program LIDAEUS.
    Taylor et al.
    Br.J.Pharmacol., 2008;153:S55
  2. Inhibitors of polo-like kinase reveal roles in spindle pole maintenance.
    McInnes et al.
    Nature Chem.Biol., 2006;2:608

The citations listed below are publications that use Tocris products. Selected citations for Cyclapolin 9 include:

Showing Results 1 - 1 of 1

  1. Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.
    Authors: Cozzoli Et al.
    Proc Natl Acad Sci U S A
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