Cyclapolin 9

Key Product Details

Product Description

Cyclapolin 9 is a selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC₅₀ = 500 nM).

Product Specifications for Cyclapolin 9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Cyclapolin 9

The following data is based on the product molecular weight 307.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	13.02 mL	65.10 mL	130.20 mL
1.25 mM	2.60 mL	13.02 mL	26.04 mL
2.5 mM	1.30 mL	6.51 mL	13.02 mL
12.5 mM	0.26 mL	1.30 mL	2.60 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• McInnes Inhibitors of polo-like kinase reveal roles in spindle pole maintenance. Nature Chem.Biol.
• Taylor Ligand discovery and virtual screening using the program LIDAEUS. Br.J.Pharmacol. 2008 PMID: 18037921

Product Documents for Cyclapolin 9