Chemical Name: 2,2'-Diaminodiethyl disulfide dihydrochloride
Biological Activity Transglutaminase inhibitor. Attenuates cell death induced by 3-nitropropionic acid (Cat. No. 4849) in Huntington's disease (HD) striatal cells. Also decreases aggregated and cross-linked huntingtin in transfected cells, and increases brain levels of BDNF. Shown to extend survival and improve motor performance in transgenic HD mice. Neuroprotective.
Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT
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