Cystamine dihydrochloride

Catalog # Availability Size / Price Qty
4981/50
Cat.No. 4981 - Cystamine dihydrochloride | C4H12N2S2.2HCl | CAS No. 56-17-7
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Description: Transglutaminase inhibitor; neuroprotective

Chemical Name: 2,2'-Diaminodiethyl disulfide dihydrochloride

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Biological Activity

Transglutaminase inhibitor. Attenuates cell death induced by 3-nitropropionic acid (Cat. No. 4849) in Huntington's disease (HD) striatal cells. Also decreases aggregated and cross-linked huntingtin in transfected cells, and increases brain levels of BDNF. Shown to extend survival and improve motor performance in transgenic HD mice. Neuroprotective.

Technical Data

M.Wt:
225.2
Formula:
C4H12N2S2.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Desiccate at RT
CAS No:
56-17-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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