Catalog Number: 1482
Biological Activity
Important second messenger involved in Ca2+ mobilization from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.
Technical Data
  • M.Wt:
    648.64
  • Formula:
    C6H9O15P3.K6
  • Solubility:
    Soluble in water
  • Storage:
    Store at -20°C
  • CAS No:
    103476-24-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. myo-Inositol 1,4,5-trisphosphate.
    Joseph et al.
    J.Biol.Chem., 1984;259:3077
  2. Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors.
    Murphy et al.
    Mol.Pharmacol., 1996;50:1223
  3. New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor.
    Wilcox et al.
    TiPS, 1998;19:467

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