Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid
Biological Activity Histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases and 2-oxoglurate oxygenases (IC50 > 100 μM).
Soluble to 100 mM in DMSO and to 100 mM in water
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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