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Daminozide

4684 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4684/50
Cat.No. 4684 - Daminozide | C6H12N2O3 | CAS No. 1596-84-5
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Description: Selective KDM2/7 inhibitor

Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid

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Biological Activity

Histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases and 2-oxoglurate oxygenases (IC50 > 100 μM).

Technical Data

M.Wt:
160.17
Formula:
C6H12N2O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in water
Storage:
Store at RT
CAS No:
1596-84-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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⚠ WARNING: This product can expose you to chemicals including Daminozide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

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