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Daminozide

   
Product Datasheet
Catalog Number:4684
Chemical Name:1-(2,2-Dimethylhydrazide)butanedioic acid
Product Details
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Biological Activity
Histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases and 2-oxoglurate oxygenases (IC50 > 100 μM).
Technical Data
  • M.Wt:
    160.17
  • Formula:
    C6H12N2O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    1596-84-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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