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Daminozide

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Daminozide | CAS No. 1596-84-5 | Histone Demethylase Inhibitors
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Description: Selective KDM2/7 inhibitor

Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid

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Biological Activity

Daminozide is a histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases and 2-oxoglurate oxygenases (IC50 > 100 μM).

Technical Data

M.Wt:
160.17
Formula:
C6H12N2O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in water
Storage:
Store at RT
CAS No:
1596-84-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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⚠ WARNING: This product can expose you to chemicals including Daminozide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

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