16 results for "Histone Demethylase Inhibitors" in Products
Histone Demethylase Inhibitors
Histone demethylases are a family of enzymes that includes lysine demethylases (KDMs) and arginine demethylases. These enzymes catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues that is catalyzed by histone methyltransferases.
The first histone demethylase to be discovered was lysine-specific demethylase 1 (LSD1), but further research identified an additional family of histone demethylases; ...
Histone KDM inhibitor; cell permeable
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% |
Irreversible inhibitor of LSD1; also inhibits MAO
| Alternate Names: | 2-PCPA |
| Chemical Name: | (±)-trans-2-Phenylcyclopropylamine hydrochloride |
| Purity: | ≥98% |
Potent JMJD3/UTX inhibitor
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine |
| Purity: | ≥98% |
Pan Jumonji inhibitor; active in vivo
| Chemical Name: | 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine |
| Purity: | ≥98% |
Pan-histone demethylase inhibitor
| Chemical Name: | 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
| Purity: | ≥98% |
Histone demethylase inhibitor; cell permeable
| Alternate Names: | 5-carboxy-8HQ |
| Chemical Name: | 8-Hydroxy-5-quinolinecarboxylic acid |
| Purity: | ≥98% |
Inactive isomer of GSK J1 (Cat. No. 4593)
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% |
LSD1 inhibitor
| Chemical Name: | 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride |
| Purity: | ≥97% |
Selective KDM2/7 inhibitor
| Chemical Name: | N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine |
| Purity: | ≥98% |
KDM4A/KDM4B inhibitor
| Chemical Name: | 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene |
| Purity: | ≥98% |
Potent and selective LSD1 inhibitor
| Chemical Name: | rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine dihydrochloride |
| Purity: | ≥98% |
LSD1 inhibitor
| Chemical Name: | (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride |
| Purity: | ≥98% |
Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride |
| Purity: | ≥98% |
Selective inhibitor of lysine demethylase 5
| Chemical Name: | 2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride |
| Purity: | ≥98% |
Lysine-Specific Demethylase 1 (LSD1) inhibitor
| Chemical Name: | 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride |
| Purity: | ≥98% |
JMJD1C inhibitor
| Chemical Name: | 8-Benzoyl-2,3,6,7-tetrahydro-5-oxo-5H-thiazolo[3,2-a]pyridine-6-acetic acid |
| Purity: | ≥98% |
