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DAPTA

   
Product Datasheet
Catalog Number:2423
Alternate Names:D-Ala-peptide T-amide
Chemical Name:
Product Details
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Biological Activity
Chemokine receptor 5 (CCR5) antagonist. Acts as a selective viral entry inhibitor for R5 tropic HIV-1 strains. Blocks CCR5-mediated monocyte chemotaxis and reduces microglia and astrocyte activation in a neuroinflammatory rat model of Alzheimer's disease.
Technical Data
  • M.Wt:
    856.89
  • Formula:
    C35H56N10O15
  • Sequence:
    ASTTTNYT

    (Modifications: Ala-1 = D-Ala, Thr-8 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    106362-34-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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