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DAPTA

2423 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2423/1
DAPTA
1 Image
Description: Chemokine receptor 5 (CCR5) antagonist
Alternative Names: D-Ala-peptide T-amide
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Biological Activity

DAPTA is a chemokine receptor 5 (CCR5) antagonist. Acts as a selective viral entry inhibitor for R5 tropic HIV-1 strains. Blocks CCR5-mediated monocyte chemotaxis and reduces microglia and astrocyte activation in a neuroinflammatory rat model of Alzheimer's disease.

Technical Data

M.Wt:
856.89
Formula:
C35H56N10O15
Sequence:
ASTTTNYT

(Modifications: Ala-1 = D-Ala, Thr-8 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
106362-34-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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FAQs

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VersaClone cDNA Plasmids

Canine CCR5 (NP_001012342) VersaClone cDNA

RDC1014

Feline CCR5 (NP_001009248) VersaClone cDNA

RDC1098

Human CCR5 (NP_000570) VersaClone cDNA

RDC0010

Mouse CCR5 (AAC52454) VersaClone cDNA

RDC0011

Mouse CCR5 (NP_034047) VersaClone cDNA

RDC1132

Rat CCR5 (O08556) VersaClone cDNA

RDC0350

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