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DAPTA

2423 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2423/1
DAPTA
1 Image
Description: Chemokine receptor 5 (CCR5) antagonist
Alternative Names: D-Ala-peptide T-amide
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Biological Activity

Chemokine receptor 5 (CCR5) antagonist. Acts as a selective viral entry inhibitor for R5 tropic HIV-1 strains. Blocks CCR5-mediated monocyte chemotaxis and reduces microglia and astrocyte activation in a neuroinflammatory rat model of Alzheimer's disease.

Technical Data

M.Wt:
856.89
Formula:
C35H56N10O15
Sequence:
ASTTTNYT

(Modifications: Ala-1 = D-Ala, Thr-8 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
106362-34-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

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VersaClone cDNA Plasmids

Rat CCR5 (O08556) VersaClone cDNA

RDC0350

Human CCR5 (NP_000570) VersaClone cDNA

RDC0010

Canine CCR5 (NP_001012342) VersaClone cDNA

RDC1014

Mouse CCR5 (NP_034047) VersaClone cDNA

RDC1132

Mouse CCR5 (AAC52454) VersaClone cDNA

RDC0011

Feline CCR5 (NP_001009248) VersaClone cDNA

RDC1098

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