28 results for "Chemokine Receptor Antagonists" in Products

Chemokine Receptor Antagonists

Highly selective CCR2 chemokine receptor antagonist

Chemical Name: 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
Purity: ≥98%
Highly selective CCR2 chemokine receptor antagonist
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Highly selective CXCR4 antagonist

Alternate Names: JM 3100,Plerixafor
Chemical Name: 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride
Highly selective CXCR4 antagonist
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Selective CCR5 antagonist

Alternate Names: UK-427857
Chemical Name: 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide
Purity: ≥98%
Selective CCR5 antagonist
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Potent and selective CCR3 antagonist

Chemical Name: N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester
Purity: ≥98%
Potent and selective CCR3 antagonist
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CXCR3 antagonist; inhibits cell migration and metastasis

Chemical Name: N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide
Purity: ≥98%
CXCR3 antagonist; inhibits cell migration and metastasis
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Potent and selective CXCR2 antagonist

Chemical Name: N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea
Purity: ≥98%
Potent and selective CXCR2 antagonist
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CCR2b chemokine receptor antagonist

Chemical Name: 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride
Purity: ≥98%
CCR2b chemokine receptor antagonist
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Potent and selective CXCR4 antagonist

Chemical Name: N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
Purity: ≥97%
Potent and selective CXCR4 antagonist
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High affinity, potent CCR2 antagonist

Chemical Name: 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
Purity: ≥98%
High affinity, potent CCR2 antagonist
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Potent CXCR2 antagonist

Chemical Name: N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea
Purity: ≥98%
Potent CXCR2 antagonist
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Potent CCR1 chemokine receptor antagonist

Chemical Name: 1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide
Purity: ≥98%
Potent CCR1 chemokine receptor antagonist
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Selective CCR1 antagonist

Alternate Names: VUF 2274
Chemical Name: 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride
Purity: ≥98%
Selective CCR1 antagonist
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Potent and selective CCR5 and CCR2 chemokine receptor antagonist

Chemical Name: N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride
Purity: ≥98%
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
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Selective CCR2 antagonist

Chemical Name: N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide dimethanesulfonate
Purity: ≥98%
Selective CCR2 antagonist
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Potent and selective CXCR3 antagonist

Chemical Name: N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide
Purity: ≥98%
Potent and selective CXCR3 antagonist
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Potent CCR1 and CCR3 antagonist

Chemical Name: 1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide
Purity: ≥98%
Potent CCR1 and CCR3 antagonist
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Potent CXCR4 antagonist

Chemical Name: N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride
Purity: ≥98%
Potent CXCR4 antagonist
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CXCR4 antagonist; antitumor

Purity: ≥95%
CXCR4 antagonist; antitumor
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Potent, selective CCR1 antagonist

Alternate Names: ZK-811752
Chemical Name: (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine
Purity: ≥98%
Potent, selective CCR1 antagonist
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Potent CCR4 antagonist

Chemical Name: 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
Purity: ≥98%
Potent CCR4 antagonist
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Potent and selective CCR3 antagonist

Chemical Name: N-Benzoyl-4-nitroaniline ethyl ester
Purity: ≥98%
Potent and selective CCR3 antagonist
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Potent CXCR2 antagonist

Chemical Name: 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Purity: ≥98%
Potent CXCR2 antagonist
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Potent CXCR2 antagonist

Chemical Name: 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one
Purity: ≥98%
Potent CXCR2 antagonist
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Potent and selective CCR10 antagonist

Chemical Name: N-[(1R)-3-(2-Cyano-1H-pyrrol-1-yl)-1-[(4-methyl-1-piperidinyl)carbonyl]propyl]-1H-indole-4-sulfonamide
Purity: ≥98%
Potent and selective CCR10 antagonist
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CX3CR1 antagonist

Chemical Name: 5-[3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl]pyrrolo[1,2-a]quinoxalin-4(5H)-one hydrochloride
Purity: ≥98%
CX3CR1 antagonist
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