DFB

  ( 1 citations )    
Product Datasheet
Catalog Number:1625
Alternate Names:3,3'-Difluorobenzaldazine
Chemical Name:[(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde
Product Details
Citations (1)
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Biological Activity
Novel allosteric potentiator of the metabotropic glutamate receptor mGlu5. Devoid of agonist activity itself, but potentiates (3 - 6-fold) the action of agonists at mGlu5 without any effect at other mGlu subtypes (EC50 for potentiation = 2 - 5.3 μM).
Technical Data
  • M.Wt:
    244.24
  • Formula:
    C14H10F2N2
  • Solubility:
    Soluble to 10 mM in ethanol and to 50 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    15332-10-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for DFB include:

1 Citations: Showing 1 - 1

  1. mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway.
    Authors: Chen Et al.
    J Biomed Sci  2011;18:19

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