Group I mGluR Modulators: Products

Potent and selective mGlu5 negative allosteric modulator (NAM)

Positive allosteric modulator of mGlu5 receptors

Positive allosteric modulator of mGlu5 receptors

Positive allosteric modulator of mGlu1 receptors

Positive allosteric modulator of group I mGlu receptors

Negative allosteric modulator of mGlu5 receptors

Selective negative allosteric modulator of mGlu3 receptors

Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist

Potent and selective positive allosteric modulator of mGlu5 receptors

Potent and selective negative allosteric modulator of mGlu1 receptors

Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable

Potent and selective negative allosteric modulator of mGlu1 receptors

Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity