DMCM hydrochloride

Catalog # Availability Size / Price Qty
3083/10
3083/50
Cat.No. 3083 - DMCM hydrochloride | C17H18N2O4.HCl | CAS No. 1215833-62-7
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Description: Benzodiazepine inverse agonist

Chemical Name: 4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester hydrochloride

Purity: ≥98%

Product Details
Citations (3)
Reviews

Biological Activity

Benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.

Technical Data

M.Wt:
350.8
Formula:
C17H18N2O4.HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1215833-62-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. DMCM: a potent convusive benzodiazepine receptor ligand.
    Petersen
    Eur.J.Pharmacol., 1983;94:117
  2. Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist.
    Conto et al.
    Pharmacol.Biochem.Behav., 2005;82:417
  3. Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats.
    Sieve et al.
    Psychopharmacol., 2001;153:180

Product Datasheets

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Citations for DMCM hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for DMCM hydrochloride include:

3 Citations: Showing 1 - 3

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