DMeOB

Catalog # Availability Size / Price Qty
1953/10
1953/50
DMeOB | CAS No. 40252-74-2 | Group I mGluR Modulators
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Description: Negative allosteric modulator of mGlu5 receptors

Chemical Name: [(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde

Purity: ≥98%

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Biological Activity

Negative allosteric modulator of the metabotropic glutamate receptor mGlu5; displays reversible non-competitive inhibition of mGlu5-mediated responses (IC50 = 3 μM).

Technical Data

M.Wt:
268.31
Formula:
C16H16N2O2
Solubility:
Soluble to 100 mM in ethanol with gentle warming and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
40252-74-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5
    O'Brien et al.
    Mol.Pharmacol., 2003;64:731

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