hh DMeOB (CAS 40252-74-2): R&D Systems
Catalog Number: 1953
Chemical Name: [(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde
Biological Activity
Negative allosteric modulator of the metabotropic glutamate receptor mGlu5; displays reversible non-competitive inhibition of mGlu5-mediated responses (IC50 = 3 μM).
Technical Data
  • M.Wt:
    268.31
  • Formula:
    C16H16N2O2
  • Solubility:
    Soluble to 100 mM in ethanol with gentle warming and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    40252-74-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5
    O'Brien et al.
    Mol.Pharmacol., 2003;64:731

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