DMP 543

  ( 1 citations )    
Product Datasheet
Catalog Number:2330
Chemical Name:10,10-bis[(2-Fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone
Product Details
Citations (1)
Reviews
Biological Activity
Acetylcholine release stimulator. Potently enhances K+-stimulated [3H]-ACh release from rat hippocampal slices (EC50 = 700 nM), and increases release of dopamine and glutamate (EC50 values are 0.25 and 0.22 μM, respectively). Orally active in vivo; increases ACh levels in rats (with a minimum effective dose of 1 mg/kg) and exerts a long duration of action. More potent than linopirdine (Cat. No. 1999) both in vitro and in vivo. Also K+ channel blocker.
Technical Data
  • M.Wt:
    412.44
  • Formula:
    C26H18F2N2O
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    160588-45-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for DMP 543 include:

1 Citations: Showing 1 - 1

  1. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus.
    Authors: Ipavec Et al.
    Pharmacol Res  2011;64:397

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