Q: Hi, I am looking for an antibody to human DUOX2 that will work on human formalin fixed paraffin embedded sections. I notice from your website that you have several recommended for WB and wondered if you have any experience of their use in other areas?

A: At this time we do not have an antibody for DUOX2 that works in IHC paraffin embedded sections. If you choose to try one in this application we have our Innovator's Reward program where we reward our customers for trying antibodies in previously untested applications and species.

DUOX2 Antibody Blocking Peptide

Novus Biologicals | Catalog # NB110-61576PEP

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Applications

Antibody Competition

View all DUOX2 Proteins and Enzymes »

Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NB110-61576. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB110-61576 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB110-61576PEP

Formulation	Peptide dissolved in dH20. Contains no BSA.
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: DUOX2

Dual oxidase 2 (DUOX2), a reduced NAD phosphate:O2 oxidoreductase flavoprotein, plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with hydrogen peroxide, which is required for hormone synthesis at the apical plasma membrane. The discovery of DUOX-2 as a novel source of hydrogen peroxide in the digestive tract, particularly in the cecum and colon, makes it a new candidate mediator of physiopathological processes.

DUOX2 antibodies may be useful tools for thyroid hormone synthesis, hormonal regulation disorders, and certian types of cancer.

Alternate Names

dual oxidase 2, dual oxidase-like domains 2, EC 1.11.1.-, EC 1.6.3.1, flavoprotein NADPH oxidase, Large NOX 2, LNOX2P138(TOX), Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, nicotinamide adenine dinucleotide phosphate oxidase, NOXEF2, p138 thyroid oxidase, P138-TOX, THOX2TDH6, Thyroid oxidase 2

Gene Symbol

DUOX2

Additional DUOX2 Products

Product Documents for DUOX2 Antibody Blocking Peptide

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Certificate of Analysis

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Product Specific Notices for DUOX2 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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